WHO recommendations

Making WHO recommendations more responsive

Recent World Health Organization (WHO) guidelines not only advise countries on what treatment to give patients and when, but also how to roll this out in countries. Priya Shetty reports.

WHO Recommendations for the production, control and regulation of human plasma for fractionation

WHO recommendations for multidrug-resistant tuberculosis.

2234 www.thelancet.com Vol 388 November 5, 2016 3 Casas EC. Experiences with short MDR-TB regimen in unstable settings. The 46th Union World Conference on Lung Health; Cape Town, South Africa; Dec 2–6, 2015. http://capetown. worldlunghealth.org/programme/ programme-by-type/sponsored-satellitesymposia/pdf/12-Sponsored-satellitesymposium.pdf (accessed June 18, 2016). 4 Casas E, Gashu T, Greig J, ...

Use of evidence in WHO recommendations.

BACKGROUND WHO regulations, dating back to 1951, emphasise the role of expert opinion in the development of recommendations. However, the organisation's guidelines, approved in 2003, emphasise the use of systematic reviews for evidence of effects, processes that allow for the explicit incorporation of other types of information (including values), and evidence-informed dissemination and impleme...

Immunological Outcomes of New Tuberculosis Vaccine Trials: WHO Panel Recommendations

The mechanisms of immune protection against human TB, a disease that causes 2 million deaths world-wide each year, are not fully known. T cell immunity is critical for protection [1,2]; therefore, the current TB vaccine, bacille Calmette-Guérin (BCG), and most new vaccines under development aim to induce this immunity. Most of these developmental vaccines [1–4] are designed to boost pre-existin...